1. CK-elevation, lactacidosis and metabolic myopathy in adult patients with diabetes

Wed, 22 Feb 2012 19:08
Hyper-CK-emia occurs in one fifth and lactacidosis in one quarter of the patients with diabetes. Hyper-CK-emia in these patients is attributable to a primary metabolic myopathy in most of the cases. Hyper-CK-emia in patients with diabetes requires further neurological diagnostic work-up (Endocrine Practice)  
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2. Clinical Utility of Creatinine- and Cystatin C-Based Definition of Renal Function for Risk Prediction of Primary Cardiovascular Events in Patients With Diabetes

Wed, 22 Feb 2012 19:07
Only the cystatin C-based CKD definition was an independent risk predictor for cardiovascular events in our diabetic study cohort and indicated a potentially better clinical utility for cardiovascular risk prediction than creatinine-based equations (Diabetes Care)  
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3. Study finds some insulin production in long-term type 1 diabetes

Wed, 22 Feb 2012 12:30
C-peptide production and beta cell functioning detected decades after disease onset (Massachusetts General Hospital)  
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4. Exenatide prolonged-release suspension for injection in combination with oral antidiabetic therapy for the treatment of type 2 diabetes

Wed, 22 Feb 2012 11:19
Prolonged-release exenatide in triple therapy regimens (that is, in combination with metformin and a sulphonylurea, or metformin and a thiazolidinedione) is recommended as a treatment option for people with type 2 diabetes as described in'Type 2 diabetes: the management of type 2 diabetes'(NICE)  
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5. Hypertensive Disorders in Pregnancy and Subsequent Diabetes Mellitus: A Retrospective Cohort Study

Tue, 21 Feb 2012 20:18
HDP women with obesity and hyperlipidemia are at an extremely high risk of diabetes mellitus. Early identification of women with HDP is needed for prevention, particularly those with other comorbidities (American Journal of Medicine)  
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6. Enrolment in primary care networks: impact on outcomes and processes of care for patients with diabetes

Tue, 21 Feb 2012 20:18
Compared with patients whose prevalent diabetes is managed outside of primary care networks, patients in primary care networks had a lower rate of diabetes-specific ambulatory care sensitive conditions, were more likely to see an ophthalmologist or optometrist and had better glycemic control (Canadian Medical Journal)  
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7. Associations of maternal A1C and glucose with pregnancy outcomes

Mon, 20 Feb 2012 19:29
On the basis of associations with adverse outcomes, these findings suggest that A1C measurement is not a useful alternative to an OGTT in pregnant women (Diabetes Care)  
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8. Integrating an Automated Diabetes Management System Into the Family Management of Children With Type 1 Diabetes

Mon, 20 Feb 2012 19:28
Using the ADMS 1–3 times/week may help children with type 1 diabetes improve glycemic control and gain diabetes self-management skills, as well as improve the BGM effect of parents (Diabetes Care)  
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9. CHMP Recommends Approval of BYETTA® for Use With Basal Insulin

Fri, 17 Feb 2012 20:12
The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion in the European Union (EU) for the expanded use of BYETTA® (exenatide twice-daily) as an add-on therapy to basal insulin, with or without metformin and/or Actos® (pioglitazone), for the treatment of type 2 diabetes in adults who have not achieved adequate glycemic control with these agents (Lilly)  
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10. Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus

Thu, 16 Feb 2012 19:23
A Clinical Practice Guideline From the American College of Physicians (Annals of Internal Medicine)  
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11. Angiotensin receptor blockers for prevention of new-onset type 2 diabetes: A meta-analysis of 59,862 patients

Thu, 16 Feb 2012 19:22
There is sufficient evidence that ARBs have beneficial effect in preventing new-onset type 2 diabetes. ARBs should be considered in patients with high risk of developing diabetes  
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12. The branching pattern of villous capillaries and structural changes of placental terminal villi in type 1 diabetes mellitus

Wed, 15 Feb 2012 19:40
It is concluded that type 1 maternal diabetes enhances the surface area of the capillary wall by elongation, enlargement of diameter and higher branching of villous capillaries and disrupts the stromal structure of terminal villi (Placenta)  
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